In the 1370s Chaucer lived in the parish – in rooms above Aldgate gatehouse.
In 1684 Daniel Defoe was married here (in a novel he depicts an horrific account of the Great Plague of 1665 when over 5000 bodies were buried in a pit dug in the churchyard).
Sir Isaac Newton lived opposite the church when he was Master of the Royal Mint. William Symington, builder of the first practical steamboat, was buried here in 1832.
Edmund Spenser the poet was born here in 1552.
Buried in the churchyard are two noblemen beheaded on Tower Hill for their part in a rebellion against King Henry VIII; Thomas, Lord Darcy and Sir Nicholas Carew. Their Renaissance monuments in alabaster are in the Baptistry.